【1.7.0.2】B 细胞谱系和表面标志表达

A diagram of a simplified development and differentiation pathway of the B cell lineage showing some distinguishing surface markers including ATCI (transmembrane activator and CAML interactor) protein and BCMA (B cell maturation antigen). The memory B cell subset is heterogeneous and includes both unswitched (CD19+, CD27+, IgM+, IgD+) and class switched (CD19+, CD27+, IgM−, IgD−) memory B cells, which were not individually reported in some of the studies analysed.

参考资料

• Memory B Cells are Major Targets for Effective Immunotherapy in Relapsing Multiple Sclerosis